Humans and DNA Ligase Essays Solution

 Humans and DNA Ligase Essays

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 Humans and DNA Ligase Essays

Essay #1

A researcher is interested in studying the human CFTR genes and decides to insert a functional human CFTR gene in a bacterial line using molecular biology methods. Before she decides to proceed with her methodology, she comes to you and asks for your opinion. In your answer consider how bacteria (Prokaryotes) differ from humans (Eukaryotes). What are the differences in RNA processing between Eukaryotes and Prokaryotes? Are there molecules or structures involved in translation or translation that may differ between these two organisms? Lastly, compare and contrast the regulation of genes between these two organisms.

Essay #2  Humans and DNA Ligase Essays

Enzymes play an important function in cellular biology. We recently discussed the following four enzymes:

1) DNA ligase
2) DNA Polymerase
3) RNA Polymerase
4) Helicase

Describe in detail the function of each of these enzymes. What process are they are part of? What nucleic acids are they in contact with? Where would they be found in a Eukaryotic cell? Additionally, describe the consequences for a nonsense mutation in the DNA sequence for each enzyme.

Humans and DNA Ligase Essays

RUBRIC
Excellent Quality 95-100%	Introduction 45-41 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.		Literature Support 91-84  points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.			Methodology 58-53 points Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met.
Average Score 50-85%	40-38 points More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided.		83-76  points Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration.			52-49  points Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met.
Poor Quality 0-45%	37-1 points The background and/or significance are missing. No search history information is provided.		75-1 points Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration.			48-1 points There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met
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